Friday, April 24, 2009

Friday April 24, 2009 (pediatric pearl day)
Extracorporeal life support in children with acute respiratory failure

Among children with acute respiratory failure higher survival to hospital discharge were seen in :

  • younger patient age;
  • fewer days of mechanical ventilation before ECLS;
  • lower PIP;
  • higher Pao2/Fio2 ratio;
  • higher pH;
  • recent era (post-1996);
  • no use of iNO; and
  • no immunocompromising diagnosis

(all p values less than .05)

These variables were obtained on the analysis of the ELSO registry (contains data from more than145 centers worldwide that contributed information on ECLS for severe respiratory or cardiac failure) contained 2,879 pediatric patients between 1 month and 19 yrs of age who were treated with ECLS for respiratory failure.



Reference:

Extracorporeal life support for severe respiratory failure in children with immune compromised conditions - Pediatric Critical Care Medicine. 9(4):380-385, July 2008.Pediatr Crit Care 2008; 9(4); 380-385

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