Tuesday April 21, 2009
Site of Action of Antimicrobials - in nutshell


Cell Wall

Beta Lactams: Penicillins, Cephalosporins, Monobactams, Carbapenems
Glycopeptides: Vancomycin
Lipopeptide (Cell Membrane): Daptomycin


Cytoplasm

Initiation Complex: Linezolid
30S Ribosome: Aminoglycosides, Tetracyclines
50S Ribosome: Macrolides/Ketolides, Chloramphenicol, Clindamycin, Quinupristin-dalfopristin


DNA Inhibitor

Metronidazole, Fluoroquinolones, TMP-SMZ, Rifampin